Sequence Analysis and Related Approaches
This open access book provides innovative methods and original applications of sequence analysis (SA) and related methods for analysing longitudinal data describing life trajectories such as professional careers, family paths, the succession of health statuses, or the time use. The applications as well as the methodological contributions propo...
Statistical Learning and Sequential Prediction
This free book will focus on theoretical aspects of Statistical Learning and Sequential Prediction. Until recently, these two subjects have been treated separately within the learning community. The course will follow a unified approach to analyzing learning in both scenarios. To make this happen, we shall bring together ideas from probability and ...
Variant Construction from Theoretical Foundation to Applications
This book presents theoretical framework and sample applications of variant construction. The first part includes the components variant logic, variant measurements, and variant maps, while the second part covers sample applications such as variation with functions, variant stream ciphers, quantum interference, classical/quantum random sequences, w...
Evolutionary Genomics
This book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sectio...
Bioinformatics for Evolutionary Biologists
This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level to enable learning by doing. Students solve the ...
Introduction to Digital Systems Design
This book has been designed for a first course on digital design for engineering and computer science students. It offers an extensive introduction on fundamental theories, from Boolean algebra and binary arithmetic to sequential networks and finite state machines, together with the essential tools to design and simulate systems composed of a contr...
Applied Bioinformatics
This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that c...
Biopython: Tutorial and Cookbook
The Biopython Project is an international association of developers tools for computational molecular biology. Python is an object oriented, interpreted,flexible language that is becoming increasingly popular for scientific computing. Python is easy to learn, hasa very clear syntax and can easily be extended with modules written in C, C++ or FORTRA...
Biotechnologies for Plant Mutation Breeding
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular charac...
Advances in Wheat Genetics: From Genome to Field
This proceedings is a collection of 46 selected papers that were presented at the 12th International Wheat Genetics Symposium (IWGS). Since the launch of the wheat genome sequencing project in 2005, the arrival of draft genome sequences has marked a new era in wheat genetics and genomics, catalyzing rapid advancement in the field. This book provide...
Micro-, Meso- and Macro-Dynamics of the Brain
How does the brain orchestrate perceptions, thoughts, and actions from the activity of its neurons? Addressing these challenging issues requires methods with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks as well as theories to advance understanding how different levels of brain dynamics int...
Measure, Integration & Real Analysis
This open access textbook welcomes students into the fundamental theory of measure, integration, and real analysis. Focusing on an accessible approach, Axler lays the foundations for further study by promoting a deep understanding of key results. Content is carefully curated to suit a single course, or two-semester sequence of courses, creating a v...
Calculus: Early Transcendentals
Calculus: Early Transcendentals, originally by D. Guichard, has been redesigned by the Lyryx editorial team. Substantial portions of the content, examples, and diagrams have been redeveloped, with additional contributions provided by experienced and practicing instructors. This approachable textbook provides a comprehensive understanding of the nec...
Electronics for Embedded Systems
This book provides semester-length coverage of electronics for embedded systems, covering most common analog and digital circuit-related issues encountered while designing embedded system hardware. It is written for students and young professionals who have basic circuit theory background and want to learn more about passive circuits, diode and bi...
Introduction to Logic Circuits & Logic Design with VHDL
This textbook introduces readers to the fundamental hardware used in modern computers. The only pre-requisite is algebra, so it can be taken by college freshman or sophomore students or even used in Advanced Placement courses in high school. This book presents both the classical approach to digital system design (i.e., pen and paper) in addition ...
Analysis for Computer Scientists
This easy-to-follow textbook/reference presents a concise introduction to mathematical analysis from an algorithmic point of view, with a particular focus on applications of analysis and aspects of mathematical modelling. The text describes the mathematical theory alongside the basic concepts and methods of numerical analysis, enriched by computer ...
Oracle Database Notes for Professionals
The Oracle Database Notes for Professionals book is compiled from Stack Overflow Documentation, the content is written by the beautiful people at Stack Overflow....
Stable Isotopes to Trace Migratory Birds and to Identify Harmful Diseases
This manuscript discusses the potentials of the approaches as mentioned below to monitor the AIVs in WMW. Molecular diagnostic platforms enable for accurate detection of the AIVs in the feces of infected birds. Similar technologies can be used to determine the bird species through DNA barcoding, enabling non-invasive research on the epidemiology of...
The Gene Ontology Handbook
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyse...
From Bilateral Arbitral Tribunals and Investment Courts to a Multilateral Investment Court
This book considers the potential setup for a future Multilateral Investment Court (MIC). The option of an MIC was first discussed by the EU Commission in 2016 and has since been made an official element of the EU Common Commercial Policy. In 2017, UNCITRAL also decided to discuss the possibility of an MIC, and on 20 March 2018, the Council of the ...
Science of Societal Safety
This book covers comprehensive but fundamental principles and concepts of disaster and accident prevention and mitigation, countermeasures, and recovery from disasters or accidents including treatment and care of the victims. Safety and security problems in our society involve not only engineering but also social, legal, economic, cultural, and psy...
Data and Text Processing for Health and Life Sciences
This book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and...
Reconsidering Constitutional Formation I National Sovereignty
Legal studies and consequently legal history focus on constitutional documents, believing in a nominalist autonomy of constitutional semantics.Reconsidering Constitutional Formation in the late 18th and 19th century, kept historic constitutions from being simply log-books for political experts through a functional approach to the interdependencies ...
Teaching and Learning of Calculus
This survey focuses on the main trends in the field of calculus education. Despite their variety, the findings reveal a cornerstone issue that is strongly linked to the formalism of calculus concepts and to the difficulties it generates in the learning and teaching process. As a complement to the main text, an extended bibliography with some of the...
Foundations of Software Science and Computation Structures
This book constitutes the proceedings of the 21st International Conference on Foundations of Software Science and Computational Structures, FOSSACS 2018, which took place in Thessaloniki, Greece, in April 2018, held as part of the European Joint Conference on Theory and Practice of Software, ETAPS 2018.The 31 papers presented in this volume were ca...
Intertwingled
This engaging volume celebrates the life and work of Theodor Holm "Ted" Nelson, a pioneer and legendary figure from the history of early computing. Presenting contributions from world-renowned computer scientists and figures from the media industry, the book delves into hypertext, the docuverse, Xanadu, and other products of Ted Nelson's ...
Biodiversity Conservation and Phylogenetic Systematics
Phylogenetic diversity is now a key concept for biodiversity conservation due to its link to option value, evolutionary potential and to the possibility of guiding conservation across scales. Present facilities for obtaining molecular sequences and metagenomes are powering this research field, rendering available detailed information of phylogeneti...
Cyber-Physical Systems of Systems
Technical Systems-of-Systems (SoS) – in the form of networked, independent constituent computing systems temporarily collaborating to achieve a well-defined objective – form the backbone of most of today's infrastructure. The energy grid, most transportation systems, the global banking industry, the water-supply system, the military equipment, ...
Do Exclusionary Rules Ensure a Fair Trial?
This open access publication discusses exclusionary rules in different criminal justice systems. It is based on the findings of a research project in comparative law with a focus on the question of whether or not a fair trial can be secured through evidence exclusion. Part I explains the legal framework in which exclusionary rules function in six l...
The Brownian Motion
This open access textbook is the first to provide Business and Economics Ph.D. students with a precise and intuitive introduction to the formal backgrounds of modern financial theory. It explains Brownian motion, random processes, measures, and Lebesgue integrals intuitively, but without sacrificing the necessary mathematical formalism, making them...
Genome Editing in Neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médec...
Bird Species
The average person can name more bird species than they think, but do we really know what a bird "species" is? This book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of b...

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