Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
This open book is licensed under a Creative Commons License (CC BY). You can download Genome Editing in Neurosciences ebook for free in PDF format (2.6 MB).
This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that c...
This collection of essays from world-renowned scholar Hans Walter Gabler contains writings from a decade and a half of retirement spent exploring textual criticism, genetic criticism, and literary criticism. In these sixteen stimulating contributions, he develops theories of textual criticism and editing that are inflected by our advance into the d...
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular charac...
This book constitutes the thoroughly refereed proceedings of the 9th International Conference on Intelligent Human Computer Interaction, IHCI 2017, held in Evry, France, in December 2017.
The 15 papers presented together with three invited papers were carefully reviewed and selected from 25 submissions. The conference is forum for the presentation...
This open access volume explores how UN peace operations are adapting to four trends in the changing global order: (1) the rebalancing of relations between states of the global North and the global South; (2) the rise of regional organisations as providers of peace; (3) the rise of violent extremism and fundamentalist non-state actors; and (4) incr...
This proceedings is a collection of 46 selected papers that were presented at the 12th International Wheat Genetics Symposium (IWGS). Since the launch of the wheat genome sequencing project in 2005, the arrival of draft genome sequences has marked a new era in wheat genetics and genomics, catalyzing rapid advancement in the field. This book provide...