MERS Coronavirus
This volume provides various techniques and methodologies currently used in the study of MERS-CoV. Chapters are divided into four parts detailing evolution and entry of MERS-coronavirus, genetic alteration and structural determination of MERS-coronavirus proteins, quantitation of virus and anti-viral factors, and mouse models for MERS -coronavirus....
Innovative Medicine
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clini...
Make Life Visible
This book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecula...
Buruli Ulcer
A major objective of this book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epide...
Etiology and Morphogenesis of Congenital Heart Disease
This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are i...
Sexual Reproduction in Animals and Plants
This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews re...
Genome Editing in Neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque M├ędec...
Stem Cells in Neuroendocrinology
This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example...
Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
This book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in...
Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
This free book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a r...
Micro-, Meso- and Macro-Connectomics of the Brain
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes 'macro-connectome' efforts to comprehensively chart long-distance pathways and functional networks; 'micro-connectome' efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and '...
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
This free book provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine....
Invent Your Own Computer Games with Python
Invent Your Own Computer Games with Python teaches you how to program in the Python language. Each chapter gives you the complete source code for a new game, and then teaches the programming concepts from the examples. Games include Guess the Number, Hangman, Tic Tac Toe, and Reversi. This book also has an introduction to making games with 2D graph...
The Linux Command Line
The Linux Command Line takes you from your very first terminal keystrokes to writing full programs in Bash, the most popular Linux shell (or command line). Along the way you'll learn the timeless skills handed down by generations of experienced, mouse-shunning gurus: file navigation, environment configuration, command chaining, pattern matching wit...
HTML5 Canvas Notes for Professionals
The HTML5 Canvas Notes for Professionals book is compiled from Stack Overflow Documentation, the content is written by the beautiful people at Stack Overflow....
The Nature of Code
How can we capture the unpredictable evolutionary and emergent properties of nature in software? How can understanding the mathematical principles behind our physical world help us to create digital worlds? This book focuses on a range of programming strategies and techniques behind computer simulations of natural systems, from elementary concepts ...