The Gene Ontology Handbook
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyse...
Diversity and Evolution of Butterfly Wing Patterns
This book facilitates an integrative understanding of the development, genetics and evolution of butterfly wing patterns. To develop a deep and realistic understanding of the diversity and evolution of butterfly wing patterns, it is essential and necessary to approach the problem from various kinds of key research fields such as "evo-devo,&quo...
Advancing the Science of Cancer in Latinos
This book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio.Latinos – the largest, youngest, and fastest-grow...
Warlike and Peaceful Societies
Are humans violent or peaceful by nature? We are both. In this ambitious and wide-ranging book, Agner Fog presents a ground-breaking new argument that explains the existence of differently organised societies using evolutionary theory. It combines natural sciences and social sciences in a way that is rarely seen. According to a concept called...
God's Babies
The human population's annual total consumption is not sustainable by one planet. This unprecedented situation calls for a reform of religious cultures that promote a large ideal family size. Many observers assume that Christianity is inevitably part of this problem because it promotes "family values" and statistically, in America and els...
Innovative Medicine
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clini...
Ranaviruses
The first book of its kind, this work discusses the global extent of ranaviruses, principles of ranavirus ecology and evolution. The research included provides guidance on designing ranavirus surveillance studies to determine risk. Ranaviruses are are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. Rana...
A Time for Metabolism and Hormones
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspe...
Projection-Based Clustering through Self-Organization and Swarm Intelligence
It covers aspects of unsupervised machine learning used for knowledge discovery in data science and introduces a data-driven approach to cluster analysis, the Databionic swarm(DBS). DBS consists of the 3D landscape visualization and clustering of data. The 3D landscape enables 3D printing of high-dimensional data structures.The clustering and numbe...
Dilated Cardiomyopathy
This book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease's pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment intera...
Etiology and Morphogenesis of Congenital Heart Disease
This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are i...
Evolutionary Genomics
This book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sectio...
Biotechnologies for Plant Mutation Breeding
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular charac...
Advances in Wheat Genetics: From Genome to Field
This proceedings is a collection of 46 selected papers that were presented at the 12th International Wheat Genetics Symposium (IWGS). Since the launch of the wheat genome sequencing project in 2005, the arrival of draft genome sequences has marked a new era in wheat genetics and genomics, catalyzing rapid advancement in the field. This book provide...
Sexual Reproduction in Animals and Plants
This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews re...
Advancing Human Assessment
​This book describes the extensive contributions made toward the advancement of human assessment by scientists from one of the world's leading research institutions, Educational Testing Service. The book's four major sections detail research and development in measurement and statistics, education policy analysis and evaluation, scientific psycho...
The Challenge of Chance
This book presents a multidisciplinary perspective on chance, with contributions from distinguished researchers in the areas of biology, cognitive neuroscience, economics, genetics, general history, law, linguistics, logic, mathematical physics, statistics, theology and philosophy. The individual chapters are bound together by a general introductio...
Genome Editing in Neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médec...
Qualitative Freedom - Autonomy in Cosmopolitan Responsibility
In the light of growing political and religious fundamentalism, this book defends the idea of freedom as paramount for the attempt to find common ethical ground in the age of globality. The book sets out to examine as yet unexhausted ways to boost the resilience of the principle of liberalism. Critically reviewing the last 200 years of the philosop...
Bird Species
The average person can name more bird species than they think, but do we really know what a bird "species" is? This book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of b...
Biomineralization
This book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of cryst...
Forensic Genetics in the Governance of Crime
This book uses a critical sociological perspective to explore contemporary ways of reformulating the governance of crime through genetics. Through the lens of scientific knowledge and genetic technology, Machado and Granja offer a unique perspective on current trends in crime governance. They explore the place and role of genetics in criminal justi...
The Potato Crop
This book provides a fresh, updated and science-based perspective on the current status and prospects of the diverse array of topics related to the potato, and was written by distinguished scientists with hands-on global experience in research aspects related to potato. The potato is the third most important global food crop in terms of consumption...
Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
This free book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a r...
Statistical Population Genomics
This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demog...
Gene Drives at Tipping Points
This open access book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered o...
The Pangenome
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study ...
Bioinformatics for Evolutionary Biologists
This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level to enable learning by doing. Students solve the ...
Plant Physiology, Development and Metabolism
This book focuses on the fundamentals of plant physiology for undergraduate and graduate students. It consists of 34 chapters divided into five major units. Unit I discusses the unique mechanisms of water and ion transport, while Unit II describes the various metabolic events essential for plant development that result from plants’ ability to cap...
Applied Bioinformatics
This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that c...
Bad Ideas About Writing
We intend this work to be less a bestiary of bad ideas about writing than an effort to name bad ideas and suggest better ones. Some of those bad ideas are quite old, such as the archetype of the inspired genius author, the five-paragraph essay, or the abuse of adjunct writing teachers. Others are much newer, such as computerized essay scoring or ga...
Human Physiology
Physiology - The word physiology is from the Ancient Greek (phusiología) and it is the study of how organisms perform their vital functions. An example is the study of how a muscle contracts or the force contracting muscles exert on the skeleton. It was introduced by French physician Jean Fernery in 1552. Physiology is built upon a tripod of scien...